| 产品名称 |
GZMB/Granzyme B Rabbit mAb |
| 来源宿主: |
Rabbit |
| 反应种属: |
Human Mouse Rat |
| 克隆类型 |
Rabbit monoclonal |
| 克隆号 |
A598 |
| 同种型 |
IgG |
| 标记 |
unconjugated |
| 纯化方式 |
Protein A affinity purified. |
| 形式 |
Liquid |
| 存储溶液 |
PBS (pH7.4),0.05% BSA,40% Glycerol. Preservative: 0.05% Sodium Azide. |
| 存储方式 |
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| 应用 |
IHC-P,mIHC |
| 使用方法 |
IHC-P 1:100-1:300; mIHC 1:100-1:300 |
| 有效期 |
one year |
| 别名 |
C11,Cathepsin G like 1,CCPI,CGL1,CSP B,CTLA 1,Granzyme 2,Granzyme B,Gzmb |
| SwissProt |
P10144 |
| 细胞定位 |
Cytoplasmic granule. |
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This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
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