| 产品名称 |
CD8 α (Y0117) Rabbit mAb |
| 来源宿主: |
Rabbit |
| 反应种属: |
Human,Mouse,Rat, |
| 克隆类型 |
Rabbit monoclonal |
| 克隆号 |
Y0117 |
| 同种型 |
IgG |
| 标记 |
unconjugated |
| 纯化方式 |
Protein A affinity purified. |
| 形式 |
Liquid |
| 存储溶液 |
PBS (pH7.4),50% Glycerol,0.05% BSA,0.05% Proclin 300 |
| 存储方式 |
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles. |
| 应用 |
WB,IHC,mIHC,IF |
| 使用方法 |
IHC 1:100-1:500;mIHC 1:100-1:500;WB 1:500-1:2500;IF 1:100-1:500 |
| 有效期 |
one year |
| 别名 |
T-cell surface glycoprotein CD8 alpha chain;T-lymphocyte differentiation antigen T8/Leu-2;CD antigen CD8a; |
| SwissProt |
P01732 |
| 细胞定位 |
Membranous |
| 分子量 |
35kD |
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The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
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